4TYG
Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase
Summary for 4TYG
| Entry DOI | 10.2210/pdb4tyg/pdb |
| Related | 4TYE 4TYI 4TYJ |
| Descriptor | Fibroblast growth factor receptor 4, ACETATE ION (3 entities in total) |
| Functional Keywords | fibroblast growth factor receptor, kinase, transferase, dovitinib, ponatinb, proteros biostructures gmbh |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Cytoplasm : P22455 |
| Total number of polymer chains | 1 |
| Total formula weight | 34866.19 |
| Authors | Lesca, E.,Lammens, A.,Huber, R.,Augustin, M. (deposition date: 2014-07-08, release date: 2014-09-24, Last modification date: 2014-12-10) |
| Primary citation | Lesca, E.,Lammens, A.,Huber, R.,Augustin, M. Structural analysis of the human fibroblast growth factor receptor 4 kinase. J.Mol.Biol., 426:3744-3756, 2014 Cited by PubMed: 25219510DOI: 10.1016/j.jmb.2014.09.004 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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