4TX9

Crystal structure of HisAp from Streptomyces sviceus with degraded ProFAR

Summary for 4TX9

Entry DOI	10.2210/pdb4tx9/pdb
Descriptor	Phosphoribosyl isomerase A, SULFATE ION, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... (4 entities in total)
Functional Keywords	tim-barrel, isomerase, structural genomics, psi-biology, midwest center for structural genomics, mcsg
Biological source	Streptomyces sviceus ATCC 29083
Total number of polymer chains	1
Total formula weight	26742.48
Authors	Michalska, K.,Verduzco-Castro, E.A.,Endres, M.,Barona-Gomez, F.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2014-07-02, release date: 2014-08-06, Last modification date: 2023-12-27)
Primary citation	Verduzco-Castro, E.A.,Michalska, K.,Endres, M.,Juarez-Vazquez, A.L.,Noda-Garcia, L.,Chang, C.,Henry, C.S.,Babnigg, G.,Joachimiak, A.,Barona-Gomez, F. Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J., 473:1141-1152, 2016 Cited by PubMed: 26929404 DOI: 10.1042/BJ20151271 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation