4TWE

Structure of ligand-free N-acetylated-alpha-linked-acidic-dipeptidase like protein (NAALADaseL)

Summary for 4TWE

Entry DOI	10.2210/pdb4twe/pdb
Descriptor	N-acetylated-alpha-linked acidic dipeptidase-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	metalloprotein, glycoprotein, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Apical cell membrane; Single-pass type II membrane protein: Q9UQQ1
Total number of polymer chains	2
Total formula weight	167674.43
Authors	Tykvart, J.,Barinka, C.,Lubkowski, J.,Sacha, P.,Konvalinka, J. (deposition date: 2014-06-30, release date: 2015-03-18, Last modification date: 2023-12-20)
Primary citation	Tykvart, J.,Barinka, C.,Svoboda, M.,Navratil, V.,Soucek, R.,Hubalek, M.,Hradilek, M.,Sacha, P.,Lubkowski, J.,Konvalinka, J. Structural and biochemical characterization of a novel aminopeptidase from human intestine. J.Biol.Chem., 290:11321-11336, 2015 Cited by PubMed: 25752612 DOI: 10.1074/jbc.M114.628149 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation