4TU8
STRUCTURE OF U2AF65 VARIANT WITH BRU5A6 DNA
Summary for 4TU8
Entry DOI | 10.2210/pdb4tu8/pdb |
Related | 4TU7 4TU9 |
Descriptor | Splicing factor U2AF 65 kDa subunit, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DA*U)-3'), 1,4-DIETHYLENE DIOXIDE, ... (8 entities in total) |
Functional Keywords | rna splicing factor, rna recognition motif, rna binding protein, rna binding protein-dna complex, rna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 44745.49 |
Authors | MCLAUGHLIN, K.J.,JENKINS, J.L.,Agrawal, A.A.,KIELKOPF, C.L. (deposition date: 2014-06-24, release date: 2014-11-26, Last modification date: 2023-12-27) |
Primary citation | Agrawal, A.A.,McLaughlin, K.J.,Jenkins, J.L.,Kielkopf, C.L. Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc.Natl.Acad.Sci.USA, 111:17420-17425, 2014 Cited by PubMed: 25422459DOI: 10.1073/pnas.1412743111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.918 Å) |
Structure validation
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