4TNW

C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation

Summary for 4TNW

Entry DOI	10.2210/pdb4tnw/pdb
Related	3RHW 3RIA 3RIF 4TNV
Descriptor	Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, Mouse monoclonal Fab fragment, heavy chain, Mouse monoclonal Fab fragment, light chain, ... (8 entities in total)
Functional Keywords	membrane protein, ligand-gated ion channel, neurotransmitter receptor, cys-loop receptor, transport protein-immune system complex, transport protein/immune system
Biological source	Caenorhabditis elegans More
Total number of polymer chains	30
Total formula weight	881904.08
Authors	Althoff, T.,Hibbs, R.E.,Banerjee, S.,Gouaux, E. (deposition date: 2014-06-05, release date: 2014-08-13, Last modification date: 2023-09-27)
Primary citation	Althoff, T.,Hibbs, R.E.,Banerjee, S.,Gouaux, E. X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors. Nature, 512:333-337, 2014 Cited by PubMed: 25143115 DOI: 10.1038/nature13669 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation