4TKP
Complex of Ubc13 with the RING domain of the TRIM5alpha retroviral restriction factor
Summary for 4TKP
Entry DOI | 10.2210/pdb4tkp/pdb |
Descriptor | Ubiquitin-conjugating enzyme E2 N, Tripartite motif-containing protein 5, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hiv restriction, trim5, ubc13, e3 ubiquitin ligase, ring dimerization, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 27773.56 |
Authors | Johnson, R.,Taylor, A.B.,Hart, P.J.,Ivanov, D.N. (deposition date: 2014-05-27, release date: 2015-07-22, Last modification date: 2023-12-27) |
Primary citation | Yudina, Z.,Roa, A.,Johnson, R.,Biris, N.,de Souza Aranha Vieira, D.A.,Tsiperson, V.,Reszka, N.,Taylor, A.B.,Hart, P.J.,Demeler, B.,Diaz-Griffero, F.,Ivanov, D.N. RING Dimerization Links Higher-Order Assembly of TRIM5 alpha to Synthesis of K63-Linked Polyubiquitin. Cell Rep, 12:788-797, 2015 Cited by PubMed: 26212332DOI: 10.1016/j.celrep.2015.06.072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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