4S3M

Evidence of kinetic cooperativity in dimeric Ketopantoate Reductase from Staphylococcus aureus

Summary for 4S3M

Entry DOI	10.2210/pdb4s3m/pdb
Related	4YCA
Descriptor	2-dehydropantoate 2-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	rossman fold, nucleotide binding domain, nadph, oxidation, oxidoreductase
Biological source	Staphylococcus aureus subsp. aureus Mu50
Total number of polymer chains	2
Total formula weight	68442.84
Authors	Sanchez, J.E.,Walsh Jr., R.M.,Wood, Z.A. (deposition date: 2015-02-19, release date: 2015-03-11, Last modification date: 2024-02-28)
Primary citation	Sanchez, J.E.,Gross, P.G.,Goetze, R.W.,Walsh Jr., R.M.,Peeples, W.B.,Wood, Z.A. Evidence of Kinetic Cooperativity in Dimeric Ketopantoate Reductase from Staphylococcus aureus. Biochemistry, 54:3360-3369, 2015 Cited by PubMed: 25946571 DOI: 10.1021/acs.biochem.5b00174 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation