4S0Q
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and carboplatin
Summary for 4S0Q
Entry DOI | 10.2210/pdb4s0q/pdb |
Descriptor | Ribonuclease pancreatic, carboplatin (3 entities in total) |
Functional Keywords | ribonuclease, rna cleavage, hydrolase-rna complex, hydrolase/rna |
Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) |
Cellular location | Secreted: P61823 |
Total number of polymer chains | 2 |
Total formula weight | 28159.15 |
Authors | Merlino, A. (deposition date: 2015-01-04, release date: 2015-11-18, Last modification date: 2023-09-20) |
Primary citation | Messori, L.,Marzo, T.,Merlino, A. Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts. J.Inorg.Biochem., 153:136-142, 2015 Cited by PubMed: 26239545DOI: 10.1016/j.jinorgbio.2015.07.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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