4RS1
Crystal structure of receptor-cytokine complex
Summary for 4RS1
Entry DOI | 10.2210/pdb4rs1/pdb |
Descriptor | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, Granulocyte-macrophage colony-stimulating factor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | cytokine, receptor, cytokine receptor-cytokine complex, cytokine receptor/cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 46278.27 |
Authors | Broughton, S.E.,Parker, M.W.,Dhagat, U. (deposition date: 2014-11-06, release date: 2015-11-11, Last modification date: 2020-07-29) |
Primary citation | Broughton, S.E.,Hercus, T.R.,Nero, T.L.,Dottore, M.,McClure, B.J.,Dhagat, U.,Taing, H.,Gorman, M.A.,King-Scott, J.,Lopez, A.F.,Parker, M.W. Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24:1271-1281, 2016 Cited by PubMed: 27396825DOI: 10.1016/j.str.2016.05.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
Download full validation report