4R7C
Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with DiMethylammonium
Summary for 4R7C
Entry DOI | 10.2210/pdb4r7c/pdb |
Related | 3K0D 3K0G 4R50 4R6Z |
Descriptor | Potassium channel protein, GLYCINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
Functional Keywords | alpha-helical membrane protein, nak-chimera channel in complex with dima+, transport protein |
Biological source | Bacillus cereus ATCC 14579 |
Total number of polymer chains | 4 |
Total formula weight | 46873.83 |
Authors | De March, M.,Napolitano, L.M.R.,Onesti, S. (deposition date: 2014-08-27, release date: 2015-07-01, Last modification date: 2023-09-20) |
Primary citation | Napolitano, L.M.,Bisha, I.,De March, M.,Marchesi, A.,Arcangeletti, M.,Demitri, N.,Mazzolini, M.,Rodriguez, A.,Magistrato, A.,Onesti, S.,Laio, A.,Torre, V. A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels. Proc.Natl.Acad.Sci.USA, 112:E3619-E3628, 2015 Cited by PubMed: 26100907DOI: 10.1073/pnas.1503334112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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