4R6X

Plasmodium falciparum phosphoethanolamine methyltransferase D128A mutant in complex with S-adenosylhomocysteine and phosphoethanolamine

Summary for 4R6X

• Entry DOI: 10.2210/pdb4r6x/pdb
• Related: 3UJ6 3UJ7 3UJ8 3UJ9 3UJA 3UJB 4R6W
• Descriptor: Phosphoethanolamine N-methyltransferase, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: methyltransferase, transferase
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 2
• Total formula weight: 61272.97

Authors

Lee, S.G.,Jez, J.M. (deposition date: 2014-08-26, release date: 2014-10-08, Last modification date: 2023-09-20)

• Primary citation: Saen-Oon, S.,Lee, S.G.,Jez, J.M.,Guallar, V.; An Alternative Mechanism for the Methylation of Phosphoethanolamine Catalyzed by Plasmodium falciparum Phosphoethanolamine Methyltransferase.; J.Biol.Chem., 289:33815-33825, 2014; PubMed: 25288796; DOI: 10.1074/jbc.M114.611319

Experimental method

X-RAY DIFFRACTION (2.5534 Å)