4R5K

Crystal structure of the DnaK C-terminus (Dnak-SBD-B)

Summary for 4R5K

• Entry DOI: 10.2210/pdb4r5k/pdb
• Descriptor: Chaperone protein DnaK, SULFATE ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: helical bundle, beta sheets, chaperone, membrane
• Biological source: Escherichia coli
• Cellular location: Cytoplasm : P0A6Y8
• Total number of polymer chains: 2
• Total formula weight: 50470.59

Authors

Leu, J.I.,Zhang, P.,Murphy, M.E.,Marmorstein, R.,George, D.L. (deposition date: 2014-08-21, release date: 2014-09-10, Last modification date: 2024-02-28)

• Primary citation: Leu, J.I.,Zhang, P.,Murphy, M.E.,Marmorstein, R.,George, D.L.; Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket.; Acs Chem.Biol., 9:2508-2516, 2014; PubMed: 25148104; DOI: 10.1021/cb500236y

Experimental method

X-RAY DIFFRACTION (1.7469 Å)