4QSY

SHP2 SH2 domain in complex with GAB1 peptide

Summary for 4QSY

• Entry DOI: 10.2210/pdb4qsy/pdb
• Descriptor: Tyrosine-protein phosphatase non-receptor type 11, GRB2-associated-binding protein 1 (3 entities in total)
• Functional Keywords: sh2 domain, signalling, ptr binding, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q06124
• Total number of polymer chains: 2
• Total formula weight: 13754.20

Authors

Gogl, G.,Remenyi, A. (deposition date: 2014-07-06, release date: 2015-07-08, Last modification date: 2023-12-06)

• Primary citation: Gogl, G.,Remenyi, A.; Selective targeting of GAB adapter protein SHP2 tyrosine phosphatase interaction attenuates ERK signaling; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)