4PUF
Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1
Summary for 4PUF
Entry DOI | 10.2210/pdb4puf/pdb |
Descriptor | E3 ubiquitin-protein ligase SlrP, Thioredoxin (2 entities in total) |
Functional Keywords | lrr domain, nel domain, e3 ubiquitin ligase, human thioredoxin 1, ligase -oxidoreductase complex, ligase-oxidoreductase complex, ligase/oxidoreductase |
Biological source | Salmonella enterica subsp. enterica serovar Typhimurium More |
Cellular location | Secreted: D0ZRB2 Nucleus: P10599 |
Total number of polymer chains | 4 |
Total formula weight | 172247.14 |
Authors | Zouhir, S.,Bernal-Bayard, J.,Cordero-Alba, M.,Cardenal-Munoz, E.,Guimaraes, B.,Lazar, N.,Ramos-Morales, F.,Nessler, S. (deposition date: 2014-03-13, release date: 2014-09-17, Last modification date: 2024-02-28) |
Primary citation | Zouhir, S.,Bernal-Bayard, J.,Cordero-Alba, M.,Cardenal-Munoz, E.,Guimaraes, B.,Lazar, N.,Ramos-Morales, F.,Nessler, S. The structure of the Slrp-Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family. Biochem.J., 464:135-144, 2014 Cited by PubMed: 25184225DOI: 10.1042/BJ20140587 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.296 Å) |
Structure validation
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