4PT6

The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities

Summary for 4PT6

• Entry DOI: 10.2210/pdb4pt6/pdb
• Descriptor: Coagulation factor VIII (2 entities in total)
• Functional Keywords: integrin binding, integrin, cell adhesion
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space: P00451
• Total number of polymer chains: 2
• Total formula weight: 38341.56

Authors

Kym, G.,Shi, K.,Kamajaya, A.,Hamdouche, S.,Kostecki, J.S.,Wannier, T.,Li, B.,Nikolovski, P.,Mayo, S.L. (deposition date: 2014-03-10, release date: 2015-04-08)

• Primary citation: Kym, G.,Shi, K.,Kamajaya, A.,Hamdouche, S.,Kostecki, J.S.,Wannier, T.,Li, B.,Nikolovski, P.,Mayo, S.L.; The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)