4PK7
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins
Summary for 4PK7
Entry DOI | 10.2210/pdb4pk7/pdb |
Descriptor | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total) |
Functional Keywords | sister chromatid cohesion, cohesin subunits, protein-protein interaction, heat repeat, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 131948.27 |
Authors | Hara, K.,Chen, Z.,Tomchick, D.R.,Yu, H. (deposition date: 2014-05-13, release date: 2014-09-03, Last modification date: 2023-09-27) |
Primary citation | Hara, K.,Zheng, G.,Qu, Q.,Liu, H.,Ouyang, Z.,Chen, Z.,Tomchick, D.R.,Yu, H. Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21:864-870, 2014 Cited by PubMed: 25173175DOI: 10.1038/nsmb.2880 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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