4PD5

Crystal structure of vcCNT-7C8C bound to gemcitabine

Summary for 4PD5

Entry DOI	10.2210/pdb4pd5/pdb
Related	3TIJ 4PB1 4PB2 4PD7 4PD8 4PD9 4PDA
Descriptor	NupC family protein, GEMCITABINE, SODIUM ION, ... (5 entities in total)
Functional Keywords	membrane protein, sodium-coupled transporter, gemcitabine, drug transporter, transport protein
Biological source	Vibrio cholerae serotype O1
Total number of polymer chains	1
Total formula weight	44920.60
Authors	Johnson, Z.L.,Lee, S.-Y. (deposition date: 2014-04-17, release date: 2014-08-13, Last modification date: 2023-09-27)
Primary citation	Johnson, Z.L.,Lee, J.H.,Lee, K.,Lee, M.,Kwon, D.Y.,Hong, J.,Lee, S.Y. Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife, 3:e03604-e03604, 2014 Cited by PubMed: 25082345 DOI: 10.7554/eLife.03604 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.906 Å)

Structure validation