4P9Z
Grb2 SH2 complexed with a pTyr-Ac6c-Asn tripeptide
Summary for 4P9Z
Entry DOI | 10.2210/pdb4p9z/pdb |
Related | 3S8O 4P9V |
Descriptor | Growth factor receptor-bound protein 2, NMI-PTR-02K-ASN-NH2, GLYCEROL, ... (6 entities in total) |
Functional Keywords | grb2 sh2, cation-pi interaction, signaling protein-antagonist complex, signaling protein/antagonist |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 14687.85 |
Authors | Clements, J.H.,Martin, S.F. (deposition date: 2014-04-06, release date: 2014-06-18, Last modification date: 2023-12-27) |
Primary citation | Myslinski, J.M.,Clements, J.H.,Martin, S.F. Protein-ligand interactions: Probing the energetics of a putative cation-pi interaction. Bioorg.Med.Chem.Lett., 24:3164-3167, 2014 Cited by PubMed: 24856058DOI: 10.1016/j.bmcl.2014.04.114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report