4P7U
Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with NDSB-201
Summary for 4P7U
Entry DOI | 10.2210/pdb4p7u/pdb |
Related | 1M9Z 1PLO 4XJJ |
Descriptor | TGF-beta receptor type-2, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE (3 entities in total) |
Functional Keywords | ndsb-201, type ii transforming growth factor beta receptor, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 12956.68 |
Authors | Wangkanont, K.,Forest, K.T. (deposition date: 2014-03-27, release date: 2015-06-24, Last modification date: 2023-09-27) |
Primary citation | Wangkanont, K.,Forest, K.T.,Kiessling, L.L. The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-beta receptor extracellular domain. Protein Expr.Purif., 115:19-25, 2015 Cited by PubMed: 26073093DOI: 10.1016/j.pep.2015.06.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.502 Å) |
Structure validation
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