4OUU

anti-MT1-MMP monoclonal antibody

Summary for 4OUU

• Entry DOI: 10.2210/pdb4ouu/pdb
• Related: 4QXU
• Descriptor: anti_MT1-MMP Heavy chain, anti_MT1-MMP light chain (2 entities in total)
• Functional Keywords: structural genomics, psi-2, protein structure initiative, israel structural proteomics center, ispc, immunoglobulin fold, hydrolase
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 4
• Total formula weight: 98239.65

Authors

Udi, Y.,Grossman, M.,Solomonov, I.,Dym, O.,Rozenberg, H.,Koziol, A.,Cuniasse, P.,Dive, V.,Arroyo, A.G.,Irit, S.,Israel Structural Proteomics Center (ISPC) (deposition date: 2014-02-19, release date: 2014-12-17, Last modification date: 2015-01-28)

• Primary citation: Udi, Y.,Grossman, M.,Solomonov, I.,Dym, O.,Rozenberg, H.,Moreno, V.,Cuniasse, P.,Dive, V.,Arroyo, A.G.,Sagi, I.; Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.; Structure, 23:104-115, 2015; PubMed: 25482542; DOI: 10.1016/j.str.2014.10.012

Experimental method

X-RAY DIFFRACTION (2.6 Å)