4OTP

Crystal structure of the catalytic domain of the human RioK1 atypical protein kinase in complex with ADP/Mg2+

Summary for 4OTP

Entry DOI	10.2210/pdb4otp/pdb
Descriptor	Serine/threonine-protein kinase RIO1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	atypical kinase domain, rio domain, ribosome biogenesis, pre-40s, preribosome, phosphorylation, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	42276.73
Authors	LaRonde, N.A.,Kiburu, I.N. (deposition date: 2014-02-14, release date: 2014-07-02, Last modification date: 2014-08-13)
Primary citation	Ferreira-Cerca, S.,Kiburu, I.,Thomson, E.,LaRonde, N.,Hurt, E. Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes. Nucleic Acids Res., 42:8635-8647, 2014 Cited by PubMed: 24948609 DOI: 10.1093/nar/gku542 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation