4OII

West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab

Summary for 4OII

• Entry DOI: 10.2210/pdb4oii/pdb
• Related: 4OIE 4OIG
• Descriptor: NON-STRUCTURAL PROTEIN NS1, Light Chain of Fab fragment of 22NS1 Antibody, Heavy Chain of Fab fragment of 22NS1 Antibody, ... (4 entities in total)
• Functional Keywords: west nile virus, antibody, fab, neutralizing, flavivirus, non-structural protein, ns1, viral protein-immune system complex, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein/immune system
• Biological source: West Nile virus (WNV); More
• Cellular location: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Lumenal side . Host nucleus . Secreted . Virion membrane ; Multi-pass membrane protein : U3N977
• Total number of polymer chains: 6
• Total formula weight: 135472.64

Authors

Edeling, M.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-01-19, release date: 2014-03-05, Last modification date: 2017-11-22)

• Primary citation: Edeling, M.A.,Diamond, M.S.,Fremont, D.H.; Structural basis of Flavivirus NS1 assembly and antibody recognition.; Proc.Natl.Acad.Sci.USA, 111:4285-4290, 2014; PubMed: 24594604; DOI: 10.1073/pnas.1322036111

Experimental method

X-RAY DIFFRACTION (3 Å)