4O7D

Crystal structure of human glutaminase in complex DON

Summary for 4O7D

• Entry DOI: 10.2210/pdb4o7d/pdb
• Descriptor: Glutaminase kidney isoform, mitochondrial, 5-OXO-L-NORLEUCINE (3 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Cytoplasm, cytosol. Isoform 3: Mitochondrion: O94925
• Total number of polymer chains: 1
• Total formula weight: 34606.51

Authors

Thangavelu, K.,Sivaraman, J. (deposition date: 2013-12-24, release date: 2014-04-16)

• Primary citation: Thangavelu, K.,Chong, Q.Y.,Low, B.C.,Sivaraman, J.; Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA); Sci Rep, 4:3827-3827, 2014; PubMed: 24451979; DOI: 10.1038/srep03827

Experimental method

X-RAY DIFFRACTION (2.3 Å)