4O58

Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin

Summary for 4O58

Entry DOI	10.2210/pdb4o58/pdb
Descriptor	Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, Fab F045-092 light chain, ... (10 entities in total)
Functional Keywords	immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus More
Cellular location	Virion membrane ; Single-pass type I membrane protein : P03435 P03435
Total number of polymer chains	4
Total formula weight	107891.14
Authors	Lee, P.S.,Wilson, I.A. (deposition date: 2013-12-19, release date: 2014-04-16, Last modification date: 2023-09-20)
Primary citation	Lee, P.S.,Ohshima, N.,Stanfield, R.L.,Yu, W.,Iba, Y.,Okuno, Y.,Kurosawa, Y.,Wilson, I.A. Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5:3614-3614, 2014 Cited by PubMed: 24717798 DOI: 10.1038/ncomms4614 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7501 Å)

Structure validation