4NZT

Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-infleunza hemagglutinin antibody CR9114 Fab

Summary for 4NZT

Entry DOI	10.2210/pdb4nzt/pdb
Related	4FQH 4NZR 4NZU
Descriptor	Protein M TD, CR9114 heavy chain, CR9114 light chain, ... (4 entities in total)
Functional Keywords	leucine-rich repeat, broad antibody-binding, block antibody-antigen union, variable region, protein binding-immune system complex, protein binding/immune system
Biological source	Mycoplasma genitalium More
Cellular location	Membrane; Single-pass membrane protein (Potential): P47523
Total number of polymer chains	3
Total formula weight	94190.02
Authors	Zhu, X.,Wilson, I.A. (deposition date: 2013-12-12, release date: 2014-02-19, Last modification date: 2023-09-20)
Primary citation	Grover, R.K.,Zhu, X.,Nieusma, T.,Jones, T.,Boero, I.,MacLeod, A.S.,Mark, A.,Niessen, S.,Kim, H.J.,Kong, L.,Assad-Garcia, N.,Kwon, K.,Chesi, M.,Smider, V.V.,Salomon, D.R.,Jelinek, D.F.,Kyle, R.A.,Pyles, R.B.,Glass, J.I.,Ward, A.B.,Wilson, I.A.,Lerner, R.A. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science, 343:656-661, 2014 Cited by PubMed: 24503852 DOI: 10.1126/science.1246135 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.497 Å)

Structure validation