4ND3
Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (l-lactic acid) and cofactor (b-nicotinamide adenine dinucleotide)
Summary for 4ND3
| Entry DOI | 10.2210/pdb4nd3/pdb |
| Related | 4ND1 4ND2 4ND4 4ND5 |
| Descriptor | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (2S)-2-HYDROXYPROPANOIC ACID, ... (5 entities in total) |
| Functional Keywords | rossmann fold, oxidoreductase, nad binding |
| Biological source | Cryptosporidium parvum |
| Total number of polymer chains | 2 |
| Total formula weight | 69462.92 |
| Authors | Chattopadhyay, D.,Cook, W.J. (deposition date: 2013-10-25, release date: 2014-12-17, Last modification date: 2023-12-06) |
| Primary citation | Cook, W.J.,Senkovich, O.,Hernandez, A.,Speed, H.,Chattopadhyay, D. Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C:608-619, 2014 Cited by PubMed: 25542170DOI: 10.1016/j.ijbiomac.2014.12.019 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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