4NBX

Crystal Structure of Clostridium difficile Toxin A fragment TcdA-A1 Bound to A20.1 VHH

Summary for 4NBX

Entry DOI	10.2210/pdb4nbx/pdb
Related	2F6E 2G7C 4NBY 4NBZ 4NC0 4NC1 4NC2
Descriptor	TcdA, A20.1 VHH (3 entities in total)
Functional Keywords	antibody-antigen complex, immune system
Biological source	Clostridium difficile More
Total number of polymer chains	2
Total formula weight	32985.44
Authors	Murase, T.,Eugenio, L.,Schorr, M.,Hussack, G.,Tanha, J.,Kitova, E.N.,Klassen, J.S.,Ng, K.K.S. (deposition date: 2013-10-23, release date: 2013-12-11, Last modification date: 2014-02-12)
Primary citation	Murase, T.,Eugenio, L.,Schorr, M.,Hussack, G.,Tanha, J.,Kitova, E.N.,Klassen, J.S.,Ng, K.K. Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. J.Biol.Chem., 289:2331-2343, 2014 Cited by PubMed: 24311789 DOI: 10.1074/jbc.M113.505917 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation