4NB3
Crystal structure of RPA70N in complex with a 3,4 dichlorophenylalanine ATRIP derived peptide
Summary for 4NB3
Entry DOI | 10.2210/pdb4nb3/pdb |
Descriptor | Replication protein A 70 kDa DNA-binding subunit, 3,4 dichlorophenylalanine ATRIP derived peptide (3 entities in total) |
Functional Keywords | ob fold, protein-protein interaction, 3, 4 dichlorophenylalanine, peptide binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P27694 |
Total number of polymer chains | 4 |
Total formula weight | 31427.78 |
Authors | Feldkamp, M.D.,Frank, A.O.,Vangamudi, B.,Souza-Fagundes, E.M.,Luzwik, J.W.,Cortez, D.,Olejniczak, O.T.,Waterson, A.G.,Rossanese, O.W.,Fesik, S.W.,Chazin, W.J. (deposition date: 2013-10-22, release date: 2014-02-26, Last modification date: 2024-07-10) |
Primary citation | Frank, A.O.,Vangamudi, B.,Feldkamp, M.D.,Souza-Fagundes, E.M.,Luzwick, J.W.,Cortez, D.,Olejniczak, E.T.,Waterson, A.G.,Rossanese, O.W.,Chazin, W.J.,Fesik, S.W. Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A. J.Med.Chem., 57:2455-2461, 2014 Cited by PubMed: 24491171DOI: 10.1021/jm401730y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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