4N6M
Crystal structure of human cystatin E/M produced in LEXSY
Summary for 4N6M
| Entry DOI | 10.2210/pdb4n6m/pdb |
| Related | 4N6L 4N6N 4N6O |
| Descriptor | Cystatin-M, SULFATE ION (3 entities in total) |
| Functional Keywords | cysteine protease inhibitor, legumain, asparaginyl endopeptidase, reactive center loop, papain, cathepsin, cancer, cystatin fold, protease inhibitor, hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: Q15828 |
| Total number of polymer chains | 2 |
| Total formula weight | 29943.83 |
| Authors | Dall, E.,Brandstetter, H. (deposition date: 2013-10-14, release date: 2015-02-18, Last modification date: 2023-09-20) |
| Primary citation | Dall, E.,Fegg, J.C.,Briza, P.,Brandstetter, H. Structure and mechanism of an aspartimide-dependent Peptide ligase in human legumain. Angew.Chem.Int.Ed.Engl., 54:2917-2921, 2015 Cited by PubMed: 25630877DOI: 10.1002/anie.201409135 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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