4N0M

Crystal structure of human C53A DJ-1 in complex with Cu

Summary for 4N0M

Entry DOI	10.2210/pdb4n0m/pdb
Related	4MNT 4N12
Descriptor	Protein DJ-1, COPPER (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	homodimer, copper binding, rossmann fold, alpha/beta protein, chaperone, oxidative stress protection, cytosol, mitochondrion, nucleus, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor: Q99497
Total number of polymer chains	1
Total formula weight	20010.60
Authors	Cendron, L.,Girotto, S.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L. (deposition date: 2013-10-02, release date: 2014-03-05, Last modification date: 2024-02-28)
Primary citation	Girotto, S.,Cendron, L.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L. DJ-1 Is a Copper Chaperone Acting on SOD1 Activation. J.Biol.Chem., 289:10887-10899, 2014 Cited by PubMed: 24567322 DOI: 10.1074/jbc.M113.535112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation