4MWF

Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C

Summary for 4MWF

Entry DOI	10.2210/pdb4mwf/pdb
Descriptor	Fab AR3C heavy chain, Fab AR3C light chain, Envelope glycoprotein E2, ... (6 entities in total)
Functional Keywords	immunoglobulin fold, hcv e2, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	146155.95
Authors	Kong, L.,Wilson, I.A.,Law, M. (deposition date: 2013-09-24, release date: 2013-12-11, Last modification date: 2020-07-29)
Primary citation	Kong, L.,Giang, E.,Nieusma, T.,Kadam, R.U.,Cogburn, K.E.,Hua, Y.,Dai, X.,Stanfield, R.L.,Burton, D.R.,Ward, A.B.,Wilson, I.A.,Law, M. Hepatitis C virus e2 envelope glycoprotein core structure. Science, 342:1090-1094, 2013 Cited by PubMed: 24288331 DOI: 10.1126/science.1243876 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.645 Å)

Structure validation