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4MTZ

Structure of XIAP-BIR1 in complex with NF023

Summary for 4MTZ
Entry DOI10.2210/pdb4mtz/pdb
DescriptorE3 ubiquitin-protein ligase XIAP, ZINC ION, SULFATE ION, ... (5 entities in total)
Functional Keywordsbir domain, anti-apoptotic, tab1, ligase-ligase inhibitor complex, ligase/ligase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total formula weight51850.61
Authors
Cossu, F.,Milani, M.,Grassi, S.,Mastrangelo, E.,Bolognesi, M. (deposition date: 2013-09-20, release date: 2014-09-24, Last modification date: 2023-09-20)
Primary citationCossu, F.,Milani, M.,Grassi, S.,Malvezzi, F.,Corti, A.,Bolognesi, M.,Mastrangelo, E.
Protein-protein interactions in nfkb pathway: novel tools to promote apoptosis in cancer therapy
To be Published,
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

220113

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