4MPS

Crystal structure of rat Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1), Northeast Structural Genomics Consortium Target RnR367A

Summary for 4MPS

• Entry DOI: 10.2210/pdb4mps/pdb
• Descriptor: Beta-galactoside alpha-2,6-sialyltransferase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: structural genomics, psi-biology, northeast structural genomics consortium, nesg, alpha-beta protein, beta-galactoside alpha-2, 6-sialyltransferase 1, transferase
• Biological source: Rattus norvegicus (brown rat,rat,rats)
• Total number of polymer chains: 2
• Total formula weight: 74137.39

Authors

Forouhar, F.,Meng, L.,Milaninia, S.,Seetharaman, J.,Su, M.,Kornhaber, G.,Montelione, G.T.,Hunt, J.F.,Moremen, K.W.,Tong, L.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2013-09-13, release date: 2013-09-25, Last modification date: 2020-07-29)

• Primary citation: Meng, L.,Forouhar, F.,Thieker, D.,Gao, Z.,Ramiah, A.,Moniz, H.,Xiang, Y.,Seetharaman, J.,Milaninia, S.,Su, M.,Bridger, R.,Veillon, L.,Azadi, P.,Kornhaber, G.,Wells, L.,Montelione, G.T.,Woods, R.J.,Tong, L.,Moremen, K.W.; Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT alpha 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION.; J.Biol.Chem., 288:34680-34698, 2013; PubMed: 24155237; DOI: 10.1074/jbc.M113.519041

Experimental method

X-RAY DIFFRACTION (2.4 Å)