4MIV
Crystal Structure of Sulfamidase, Crystal Form L
Summary for 4MIV
Entry DOI | 10.2210/pdb4miv/pdb |
Related | 4MHX |
Descriptor | N-sulphoglucosamine sulphohydrolase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | sulfatase fold, heparan, heparin, lysosome, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome: P51688 |
Total number of polymer chains | 8 |
Total formula weight | 473849.73 |
Authors | Sidhu, N.S.,Uson, I.,Schreiber, K.,Proepper, K.,Becker, S.,Sheldrick, G.M.,Gaertner, J.,Kraetzner, R.,Steinfeld, R. (deposition date: 2013-09-02, release date: 2014-05-14, Last modification date: 2021-06-02) |
Primary citation | Sidhu, N.S.,Schreiber, K.,Propper, K.,Becker, S.,Uson, I.,Sheldrick, G.M.,Gartner, J.,Kratzner, R.,Steinfeld, R. Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA. Acta Crystallogr.,Sect.D, 70:1321-1335, 2014 Cited by PubMed: 24816101DOI: 10.1107/S1399004714002739 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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