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4M9N

DNA Polymerase Beta E295K Soaked with dATP

Summary for 4M9N

Related4M9G 4M9H 4M9J 4M9L 
DescriptorDNA polymerase beta (E.C.2.7.7.7, 4.2.99.-)
Functional KeywordsDNA Polymerase, Lyase, DNA complex, TRANSFERASE-DNA complex,TRANSFERASE/DNA
Biological sourceHomo sapiens (human)
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Cellular locationNucleus 
Organ source
Total number of polymer chains4
Total molecular weight48253.86
Authors
Eckenroth, B.E.,Doublie, S. (deposition date: 2013-08-14, release date: 2013-10-16, modification date: 2013-12-18)
Primary citation
Eckenroth, B.E.,Towle-Weicksel, J.B.,Sweasy, J.B.,Doublie, S.
The E295K Cancer Variant of Human Polymerase beta Favors the Mismatch Conformational Pathway during Nucleotide Selection.
J.Biol.Chem., 288:34850-34860, 2013
PubMed: 24133209
DOI: 10.1074/jbc.M113.510891
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.275 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227301.2%3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolutionDownload full validation report

More Asymmetric unit images

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rotated about x axis by 90°
rotated about y axis by 90°
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104537
entries available on 2014-10-29
00:00 UTC / 09:00 JST