4M7C
Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2
Summary for 4M7C
Entry DOI | 10.2210/pdb4m7c/pdb |
Related | 4M79 |
Descriptor | Telomeric repeat-binding factor 2, Peptide from Structure-specific endonuclease subunit SLX4 (3 entities in total) |
Functional Keywords | telomere, t-loop, endonuclease, alt, transcription, endonuclease regulator, dna, hydrolase regulator |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q15554 Q8IY92 |
Total number of polymer chains | 4 |
Total formula weight | 49842.01 |
Authors | |
Primary citation | Wan, B.,Yin, J.,Horvath, K.,Sarkar, J.,Chen, Y.,Wu, J.,Wan, K.,Lu, J.,Gu, P.,Yu, E.Y.,Lue, N.F.,Chang, S.,Liu, Y.,Lei, M. SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres Cell Rep, 4:861-869, 2013 Cited by PubMed: 24012755DOI: 10.1016/j.celrep.2013.08.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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