4L6B

Endothiapepsin in complex with thiophen-based inhibitor SAP128

Summary for 4L6B

• Entry DOI: 10.2210/pdb4l6b/pdb
• Related: 3T7X 4LAP
• Descriptor: Endothiapepsin, DIMETHYL SULFOXIDE, N-ethyl-2-({N-[2-(1H-indol-3-yl)ethyl]glycyl}amino)-4-phenylthiophene-3-carboxamide, ... (5 entities in total)
• Functional Keywords: aspartate protease, inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Cryphonectria parasitica (Chesnut blight fungus)
• Total number of polymer chains: 1
• Total formula weight: 34508.78

Authors

Park, A.,Heine, A.,Klebe, G. (deposition date: 2013-06-12, release date: 2014-06-18)

• Primary citation: Kuhnert, M.,Park, A.,Heine, A.,Klebe, G.,Diederich, W.E.; Endothiapepsin in Complex with Thiophen based Inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (1.37 Å)