4L5F

Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII

Summary for 4L5F

• Entry DOI: 10.2210/pdb4l5f/pdb
• Descriptor: Heavy chain of E106 antibody (VH and CH1 of IgG2c), Envelope protein, Light chain of E106 antibody (kappa), ... (4 entities in total)
• Functional Keywords: antibody, fab, neutralizing, virus, envelope, viral protein, immune system, antibody epitope, infectious disease, center for structural genomics of infectious diseases (csgid), niaid, national institute of allergy and infectious diseases
• Biological source: Dengue virus 1; More
• Cellular location: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Lumenal side . Host nucleus . Secreted . Virion membrane ; Multi-pass membrane protein : Q8BE40
• Total number of polymer chains: 3
• Total formula weight: 59089.08

Authors

Edeling, M.A.,Nelson, C.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2013-06-11, release date: 2013-12-11, Last modification date: 2017-11-15)

• Primary citation: Edeling, M.A.,Austin, S.K.,Shrestha, B.,Dowd, K.A.,Mukherjee, S.,Nelson, C.A.,Johnson, S.,Mabila, M.N.,Christian, E.A.,Rucker, J.,Pierson, T.C.,Diamond, M.S.,Fremont, D.H.; Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII; To be Published,

Experimental method

X-RAY DIFFRACTION (2.45 Å)