4L0P

Structure of the human EphA3 receptor ligand binding domain complexed with ephrin-A5

Summary for 4L0P

Entry DOI	10.2210/pdb4l0p/pdb
Descriptor	Ephrin type-A receptor 3, Ephrin-A5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	beta-sandwich, receptor tyrosine kinase, ephrin binding, transferase-transferase receptor complex, transferase/transferase receptor
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	37925.40
Authors	Forse, G.J.,Kolatkar, A.R.,Kuhn, P. (deposition date: 2013-05-31, release date: 2014-06-11, Last modification date: 2023-09-20)
Primary citation	Forse, G.J.,Uson, M.L.,Nasertorabi, F.,Kolatkar, A.,Lamberto, I.,Pasquale, E.B.,Kuhn, P. Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5. Plos One, 10:e0127081-e0127081, 2015 Cited by PubMed: 25993310 DOI: 10.1371/journal.pone.0127081 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation