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4KXT

Structure of human ARGONAUTE1 in complex with guide RNA

Summary for 4KXT
Entry DOI10.2210/pdb4kxt/pdb
DescriptorProtein argonaute-1, RNA (3 entities in total)
Functional Keywordsrnase h fold, nuclease, rna, hydrolase-rna complex, hydrolase/rna
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm, P-body: Q9UL18
Total number of polymer chains2
Total formula weight101612.17
Authors
Nakanishi, K.,Patel, D.J. (deposition date: 2013-05-28, release date: 2013-07-31, Last modification date: 2024-02-28)
Primary citationNakanishi, K.,Ascano, M.,Gogakos, T.,Ishibe-Murakami, S.,Serganov, A.A.,Briskin, D.,Morozov, P.,Tuschl, T.,Patel, D.J.
Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity.
Cell Rep, 3:1893-1900, 2013
Cited by
PubMed: 23809764
DOI: 10.1016/j.celrep.2013.06.010
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.294 Å)
Structure validation

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