Summary for 4KVP
| Entry DOI | 10.2210/pdb4kvp/pdb |
| Related | 2QVQ 2QXB |
| Descriptor | Cellular tumor antigen p53, ZINC ION (3 entities in total) |
| Functional Keywords | tumor suppressor protein p53, cancer mutation, tumor, protein stability, mutant proteins, apoptosis |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 99085.64 |
| Authors | Wallentine, B.D.,Wang, Y.,Luecke, H. (deposition date: 2013-05-22, release date: 2013-07-31, Last modification date: 2024-02-28) |
| Primary citation | Wallentine, B.D.,Wang, Y.,Tretyachenko-Ladokhina, V.,Tan, M.,Senear, D.F.,Luecke, H. Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue. Acta Crystallogr.,Sect.D, 69:2146-2156, 2013 Cited by PubMed: 24100332DOI: 10.1107/S0907444913020830 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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