4KV0
Crystal structure of human carbonic anhydrase II in complex with the 5-(3-tosylureido)pyridine-2-sulfonamide inhibitor
Summary for 4KV0
| Entry DOI | 10.2210/pdb4kv0/pdb |
| Related | 4KUV 4KUW 4KUY |
| Descriptor | Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29538.68 |
| Authors | Ferraroni, M. (deposition date: 2013-05-22, release date: 2014-06-25, Last modification date: 2023-09-20) |
| Primary citation | Bozdag, M.,Ferraroni, M.,Nuti, E.,Vullo, D.,Rossello, A.,Carta, F.,Scozzafava, A.,Supuran, C.T. Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies. Bioorg.Med.Chem., 22:334-340, 2014 Cited by PubMed: 24300919DOI: 10.1016/j.bmc.2013.11.016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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