4KGC

Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM

Summary for 4KGC

• Entry DOI: 10.2210/pdb4kgc/pdb
• Descriptor: Histone H3.2, Histone H4, Histone H2A, ... (9 entities in total)
• Functional Keywords: dna-protein complex, nucleosome, ruthenium agents, structural protein-dna complex, structural protein/dna
• Biological source: Xenopus laevis (clawed frog,common platanna,platanna); More
• Cellular location: Nucleus: P84233 P62799 P02281; Chromosome . Nucleus : Q6AZJ8
• Total number of polymer chains: 10
• Total formula weight: 200792.86

Authors

Adhireksan, Z.,Davey, C.A. (deposition date: 2013-04-29, release date: 2014-03-26, Last modification date: 2024-03-20)

• Primary citation: Adhireksan, Z.,Davey, G.E.,Campomanes, P.,Groessl, M.,Clavel, C.M.,Yu, H.,Nazarov, A.A.,Yeo, C.H.,Ang, W.H.,Droge, P.,Rothlisberger, U.,Dyson, P.J.,Davey, C.A.; Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity; Nat Commun, 5:3462-3462, 2014; PubMed: 24637564; DOI: 10.1038/ncomms4462

Experimental method

X-RAY DIFFRACTION (2.69 Å)