4KC9

Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism

Summary for 4KC9

Entry DOI	10.2210/pdb4kc9/pdb
Related	4KBL
Descriptor	E3 ubiquitin-protein ligase ARIH1, ZINC ION (2 entities in total)
Functional Keywords	ring-ibr-ring, e3 ubiquitin ligase, ligase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9Y4X5
Total number of polymer chains	1
Total formula weight	65484.68
Authors	Duda, D.M.,Olszewski, J.L.,Schulman, B.A. (deposition date: 2013-04-24, release date: 2013-05-29, Last modification date: 2013-07-03)
Primary citation	Duda, D.M.,Olszewski, J.L.,Schuermann, J.P.,Kurinov, I.,Miller, D.J.,Nourse, A.,Alpi, A.F.,Schulman, B.A. Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21:1030-1041, 2013 Cited by PubMed: 23707686 DOI: 10.1016/j.str.2013.04.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.603 Å)

Structure validation