4K8R
An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo
Summary for 4K8R
Entry DOI | 10.2210/pdb4k8r/pdb |
Related | 4LKC |
Descriptor | Proprotein convertase subtilisin/kexin type 9, Fab1, light chain, Fab1, heavy chain, ... (7 entities in total) |
Functional Keywords | immunoglobulin, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 165247.47 |
Authors | Schiele, F.,Nar, H. (deposition date: 2013-04-18, release date: 2013-05-08, Last modification date: 2019-08-21) |
Primary citation | Schiele, F.,Park, J.,Redemann, N.,Luippold, G.,Nar, H. An Antibody against the C-Terminal Domain of PCSK9 Lowers LDL Cholesterol Levels In Vivo. J.Mol.Biol., 426:843-852, 2014 Cited by PubMed: 24252255DOI: 10.1016/j.jmb.2013.11.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.22 Å) |
Structure validation
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