4K7A

Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil

Summary for 4K7A

• Entry DOI: 10.2210/pdb4k7a/pdb
• Descriptor: Androgen receptor, 5-ALPHA-DIHYDROTESTOSTERONE, 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE, ... (4 entities in total)
• Functional Keywords: aandrogen receptor, ligand binding domain(lbd), steroid receptor coactivator, 5-alpha-dihydrotestosterone(dht), prostate cancer, transcription factor, coactivator binding, cytosol, nucleas, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P10275
• Total number of polymer chains: 1
• Total formula weight: 29459.64

Authors

Liu, J.S.,Hsu, C.L.,Wu, W.G. (deposition date: 2013-04-16, release date: 2014-04-16, Last modification date: 2023-11-08)

• Primary citation: Liu, J.S.,Hsu, C.L.,Wu, W.G.; Crystal structure of the androgen receptor ligand binding domain in complex with minoxidil; To be Published,

Experimental method

X-RAY DIFFRACTION (2.44 Å)