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4K31

Crystal structure of apramycin bound to the leishmanial rRNA A-site

Summary for 4K31

Related4K32 
Descriptor5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*UP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3'
Functional KeywordsrRNA duplex, Ribosomal A-site, Aminoglycoside, Ribosome, RNA, RNA-antibiotic complex,RNA/antibiotic
Biological sourceLeishmania
Total number of polymer chains2
Total molecular weight16871.21
Authors
Shalev, M.,Kondo, J.,Adir, N.,Baasov, T. (deposition date: 2013-04-10, release date: 2013-07-31, modification date: 2013-09-04)
Primary citation
Shalev, M.,Kondo, J.,Kopelyanskiy, D.,Jaffe, C.L.,Adir, N.,Baasov, T.
Identification of the molecular attributes required for aminoglycoside activity against Leishmania.
Proc.Natl.Acad.Sci.USA, 110:13333-13338, 2013
PubMed: 23898171
DOI: 10.1073/pnas.1307365110
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.415 Å)

More Asymmetric unit images

no rotation
rotated about x axis by 90°
rotated about y axis by 90°
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103557
entries available on 2014-09-24
00:00 UTC / 09:00 JST