4K2U

Crystal structure of PfEBA-175 F1 in complex with R218 antibody Fab fragment

Summary for 4K2U

• Entry DOI: 10.2210/pdb4k2u/pdb
• Related: 4K4M
• Descriptor: Erythrocyte binding antigen 175, Antibody Heavy Chain, Antibody Light Chain, ... (5 entities in total)
• Functional Keywords: dbl domain, immunoglobulin domain, antibody fragment, cell attachment, immunity, receptor, ligand, extracellular, immune system
• Biological source: Plasmodium falciparum; More
• Total number of polymer chains: 6
• Total formula weight: 174045.27

Authors

Tolia, N.H. (deposition date: 2013-04-09, release date: 2013-06-12, Last modification date: 2017-11-15)

• Primary citation: Chen, E.,Paing, M.M.,Salinas, N.,Sim, B.K.,Tolia, N.H.; Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.; Plos Pathog., 9:e1003390-e1003390, 2013; PubMed: 23717209; DOI: 10.1371/journal.ppat.1003390

Experimental method

X-RAY DIFFRACTION (2.45 Å)