4K0W

X-ray crystal structure of OXA-23 A220 duplication clinical variant

Summary for 4K0W

• Entry DOI: 10.2210/pdb4k0w/pdb
• Related: 4K0X
• Descriptor: Beta-lactamase, CITRIC ACID, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: hydrolase, carbapenemase, cephalosporinase
• Biological source: Acinetobacter baumannii
• Total number of polymer chains: 1
• Total formula weight: 28517.43

Authors

Kaitany, K.J.,Klinger, N.V.,Leonard, D.A.,Powers, R.A. (deposition date: 2013-04-04, release date: 2013-08-07, Last modification date: 2024-02-28)

• Primary citation: Kaitany, K.C.,Klinger, N.V.,June, C.M.,Ramey, M.E.,Bonomo, R.A.,Powers, R.A.,Leonard, D.A.; Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam.; Antimicrob.Agents Chemother., 57:4848-4855, 2013; PubMed: 23877677; DOI: 10.1128/AAC.00762-13

Experimental method

X-RAY DIFFRACTION (1.2 Å)