4JZW

Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in P212121 space group

Summary for 4JZW

Entry DOI	10.2210/pdb4jzw/pdb
Related PRD ID	PRD_001094
Descriptor	HIV-1 YU2 gp120 glycoprotein, CD4-MIMETIC MINIPROTEIN M48U1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	glycoprotein, hiv-1 attachment glycoprotein, cd4-mimetic miniprotein, cd4, hiv-1 envelope, viral protein-inhibitor complex, viral protein/inhibitor
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	4
Total formula weight	94221.12
Authors	Acharya, P.,Kwong, P.D. (deposition date: 2013-04-03, release date: 2013-06-12, Last modification date: 2020-07-29)
Primary citation	Acharya, P.,Luongo, T.S.,Louder, M.K.,McKee, K.,Yang, Y.,Do Kwon, Y.,Mascola, J.R.,Kessler, P.,Martin, L.,Kwong, P.D. Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1. Structure, 21:1018-1029, 2013 Cited by PubMed: 23707685 DOI: 10.1016/j.str.2013.04.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.784 Å)

Structure validation